When we try to grasp ourselves realistically and holistically, we cannot ignore the fact that we human beings are also somehow irrational and incomprehensible beings who are producing that which has to be defined as "evils", even though we are bestowed with intelligence and reasoning power as well as intuition and insight. Therefore he who does not truly know "sadness, wailing, and suffering" connected with this fact would not ever be able to taste the power and grace found in our Kairoi.
When I was about to leave Japan to study in the U.S. almost a half century ago, a friend of mine presented to me a dictionary of philosophy and wrote the following words of Goethe on the first page spread.

James Greer, the closest American friend of mine, with whom I used to live in a shabby apartment in New York, once played for me quite fervently Beethoven's sonata "Pathetique" and asked me with a serious look a question I can never forget: "Have you ever suffered?" I shrank back for a second. Then he said with a warm smile. "Forgive me. Everybody suffers".
Even though I was born in a family whose religion was Jodo Shinshu, I had never read writings of Shinran, its founder seriously. I started reading his famous book "Kyo-Gyo-Shin-Sho" (Teaching- Practice - Faith - Witness) for the first time in my life in the grand library of Columbia University. One famous passage of his remains ever fresh in my mind since then.

I never could truly perceive the depth and seriousness of these words then as an arrogant twenty three years old youth who had felt as if I had already experienced a lot of pains and sorrows of life. Now that I am over seventy years old, I hope I can slightly better conceive the depth and seriousness of these words. If so, getting old is a true blessing I should be grateful for. The Japanese expression "Arigatai" meaning "thanks" originally means: " It is hard for things to be that way". Indeed, it is not easy to learn true appreciation of anything deep.

We should be grateful (It is hard for us to feel so) that in each Chronos dwells a moment for Kairos. Yet all Kairoi are not in the same depth and weight. If I am asked now: "What is your greatest Kairos?" or "What are your greatest Kairoi?", I answer quite honestly and simply, joining billions of people in the history of the humanity, though it might sound a bit snobbish and mediocre: "That I have encountered Jesus of Nazareth and Gautama Buddha". Needless to say, though, this Jesus of Nazareth is not "Jesus Christ" absolutized as the ultimate, exclusive and supernatural divinity clad with the self-righteous and petrified "Dogma" of the orthodox Church, which inescapably is one of many human-made and therefore inevitably frail and relative organizations. And this Gautama Buddha is not the "betrayed" and deified one as a supernatural being as if he had been one of many gods in the Hindu pantheon, and who had been turned into an idol used by many corrupt so-called "Buddhist" temples of Japan. Such deities have been "dead" and "non-existent" from the very beginning anyway. And if such deities are still alive, we had better "kill" them, as some Zen masters say! If we want to follow Jesus of Nazareth who had turned over the tables of money-changers in the Temple, and Gautama Buddha who had denied Brahmans, Caste System and Transmigration and live and act in their steps, we could not avoid to declare our will to that effect. Zen tradition admonishes us to be ready to "kill" even Buddha and our ancestors!
I don't want to sound like a braggart, though. I must, therefore, talk about my own "precious kairoi", too. Karl Barth, a famous Swiss Protestant theologian who had shown me a great kairos, once left unforgettable words of wisdom about marriage by saying: "Marriage is a field where we have to learn how big many petty matters are, and how petty so-called big matters are!". This is indeed a significant wisdom to be often reminded of. And the fact that my wife and I were given our own children and now our own grandchildren who are "the cutest ones in the whole world" is truly a great kairos and a special blessing! A fine American young lady who has married my second son gave me sometime ago a coffee mug on which a statement was written: "Ask me about my grandchildren!" She wanted to tease me of my "truly objective" judgement about our grandchildren!
I recall Ralph Waldo Emerson's "Recipe For Success" as words of wisdom that promote us to live "kairos-wise" in the midst of chronoi.